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Atomic resolution protein allostery from the multi-state structure of a PDZ domain

Recent methodological advances in solution NMR allow the determination of multi-state protein structures and provide insights into structurally and dynamically correlated protein sites at atomic resolution. This is demonstrated in the present work for the well-studied PDZ2 domain of protein human ty...

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Detalles Bibliográficos
Autores principales: Ashkinadze, Dzmitry, Kadavath, Harindranath, Pokharna, Aditya, Chi, Celestine N., Friedmann, Michael, Strotz, Dean, Kumari, Pratibha, Minges, Martina, Cadalbert, Riccardo, Königl, Stefan, Güntert, Peter, Vögeli, Beat, Riek, Roland
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9584909/
https://www.ncbi.nlm.nih.gov/pubmed/36266302
http://dx.doi.org/10.1038/s41467-022-33687-x