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High-fat diet induced cyclophilin B enhances STAT3/lncRNA-PVT1 feedforward loop and promotes growth and metastasis in colorectal cancer

High-fat diet (HFD) has been implicated to promote colorectal cancer (CRC). Recently, oncogene Cyclophilin B (CypB) is reported to be induced by cholesterol. However, the role of CypB in CRC carcinogenesis and metastasis associated with HFD remains unknown. In the present study, we showed that HFD-i...

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Detalles Bibliográficos
Autores principales: Guo, Hanqing, Zhuang, Kun, Ding, Ning, Hua, Rui, Tang, Hailing, Wu, Yue, Yuan, Zuyi, Li, Ting, He, Shuixiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9584950/
https://www.ncbi.nlm.nih.gov/pubmed/36266267
http://dx.doi.org/10.1038/s41419-022-05328-0