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Brain volume in chronic ketamine users — relationship to sub-threshold psychotic symptoms and relevance to schizophrenia

RATIONALE: Ketamine may model aspects of schizophrenia arising through NMDA receptor activity deficits. Although acute ketamine can induce effects resembling both positive and negative psychotic symptoms, chronic use may be a closer model of idiopathic psychosis. OBJECTIVES: We tested the hypotheses...

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Detalles Bibliográficos
Autores principales: Chesters, Robert A., Pepper, Fiona, Morgan, Celia, Cooper, Jonathan D., Howes, Oliver D., Vernon, Anthony C., Stone, James M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9584979/
https://www.ncbi.nlm.nih.gov/pubmed/34228135
http://dx.doi.org/10.1007/s00213-021-05873-0