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Additive pharmacological interaction between sirtuin inhibitor cambinol and paclitaxel in MCF7 luminal and MDA-MB-231 triple-negative breast cancer cells

BACKGROUND: Breast cancer (BC) is the most common malignancy and the leading cause of cancer-related death in women worldwide. Sirtuin inhibitors (SIRTi), belonging to the histone deacetylase inhibitors group (HDIs), are potent epigenetic drugs that have been investigated for therapeutic use in diff...

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Detalles Bibliográficos
Autores principales: Wawruszak, Anna, Okon, Estera, Telejko, Ilona, Czerwonka, Arkadiusz, Luszczki, Jarogniew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9585000/
https://www.ncbi.nlm.nih.gov/pubmed/35900723
http://dx.doi.org/10.1007/s43440-022-00393-w