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Interaction between moxifloxacin and Mcl-1 and MITF proteins: the effect on growth inhibition and apoptosis in MDA-MB-231 human triple-negative breast cancer cells

BACKGROUND: Microphthalmia-associated transcription factor (MITF) activates the expression of genes involved in cellular proliferation, DNA replication, and repair, whereas Mcl-1 is a member of the Bcl-2 family of proteins that promotes cell survival by preventing apoptosis. The objective of the pre...

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Detalles Bibliográficos
Autores principales: Beberok, Artur, Rok, Jakub, Rzepka, Zuzanna, Marciniec, Krzysztof, Boryczka, Stanisław, Wrześniok, Dorota
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9585003/
https://www.ncbi.nlm.nih.gov/pubmed/36045272
http://dx.doi.org/10.1007/s43440-022-00407-7