Bipolar cell targeted optogenetic gene therapy restores parallel retinal signaling and high-level vision in the degenerated retina

Optogenetic gene therapies to restore vision are in clinical trials. Whilst current clinical approaches target the ganglion cells, the output neurons of the retina, new molecular tools enable efficient targeting of the first order retinal interneurons, the bipolar cells, with the potential to restor...

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Detalles Bibliográficos
Autores principales: Kralik, Jakub, van Wyk, Michiel, Stocker, Nino, Kleinlogel, Sonja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9585040/
https://www.ncbi.nlm.nih.gov/pubmed/36266533
http://dx.doi.org/10.1038/s42003-022-04016-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9585040/
https://www.ncbi.nlm.nih.gov/pubmed/36266533
http://dx.doi.org/10.1038/s42003-022-04016-1

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