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Bipolar cell targeted optogenetic gene therapy restores parallel retinal signaling and high-level vision in the degenerated retina
Optogenetic gene therapies to restore vision are in clinical trials. Whilst current clinical approaches target the ganglion cells, the output neurons of the retina, new molecular tools enable efficient targeting of the first order retinal interneurons, the bipolar cells, with the potential to restor...
Autores principales: | Kralik, Jakub, van Wyk, Michiel, Stocker, Nino, Kleinlogel, Sonja |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9585040/ https://www.ncbi.nlm.nih.gov/pubmed/36266533 http://dx.doi.org/10.1038/s42003-022-04016-1 |
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