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Myogenic tissue nanotransfection improves muscle torque recovery following volumetric muscle loss

This work rests on our non-viral tissue nanotransfection (TNT) platform to deliver MyoD (TNT(MyoD)) to injured tissue in vivo. TNT(MyoD) was performed on skin and successfully induced expression of myogenic factors. TNT(MyoD) was then used as a therapy 7 days following volumetric muscle loss (VML) o...

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Detalles Bibliográficos
Autores principales: Clark, Andrew, Ghatak, Subhadip, Guda, Poornachander Reddy, El Masry, Mohamed S., Xuan, Yi, Sato, Amy Y., Bellido, Teresita, Sen, Chandan K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9585072/
https://www.ncbi.nlm.nih.gov/pubmed/36266362
http://dx.doi.org/10.1038/s41536-022-00259-y