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Structural insight into the ligand binding mechanism of aryl hydrocarbon receptor

The aryl hydrocarbon receptor (AHR), a member of the basic helix–loop–helix (bHLH) Per–Arnt–Sim (PAS) family of transcription factors, plays important roles in regulating xenobiotic metabolism, cellular differentiation, stem cell maintenance, as well as immunity. More recently, AHR has gained signif...

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Detalles Bibliográficos
Autores principales: Dai, Shuyan, Qu, Lingzhi, Li, Jun, Zhang, Ye, Jiang, Longying, Wei, Hudie, Guo, Ming, Chen, Xiaojuan, Chen, Yongheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9585082/
https://www.ncbi.nlm.nih.gov/pubmed/36266304
http://dx.doi.org/10.1038/s41467-022-33858-w