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WTAP mediates the anti-inflammatory effect of Astragalus mongholicus polysaccharide on THP-1 macrophages

Background: Astragalus mongholicus polysaccharides (APS) have anti-inflammatory, antioxidant and immunomodulatory effects. Recent studies have demonstrated the epigenetic regulation of N6-methyladenosine (m(6)A) in the development of inflammation. However, the effect of APS on m(6)A modification is...

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Detalles Bibliográficos
Autores principales: Long, Haijiao, Lin, Haiyue, Zheng, Pan, Hou, Lianjie, Zhang, Ming, Lin, Shuyun, Yin, Kai, Zhao, Guojun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9585178/
https://www.ncbi.nlm.nih.gov/pubmed/36278233
http://dx.doi.org/10.3389/fphar.2022.1023878