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Calycosin attenuates renal ischemia/reperfusion injury by suppressing NF-κB mediated inflammation via PPARγ/EGR1 pathway

Renal ischemia reperfusion injury (IRI) is a leading and common cause of acute kidney injury (AKI), and inflammation is a critical factor in ischemic AKI progression. Calycosin (CAL), a major active component of Radix astragali, has been reported to have anti-inflammatory effect in multiple organs....

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Detalles Bibliográficos
Autores principales: Zhang, Ningxin, Guan, Chen, Liu, Zengying, Li, Chenyu, Yang, Chengyu, Xu, Lingyu, Niu, Meng, Zhao, Long, Zhou, Bin, Che, Lin, Wang, Yanfei, Xu, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9585199/
https://www.ncbi.nlm.nih.gov/pubmed/36278223
http://dx.doi.org/10.3389/fphar.2022.970616