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A novel hypoxia- and lactate metabolism-related signature to predict prognosis and immunotherapy responses for breast cancer by integrating machine learning and bioinformatic analyses

BACKGROUND: Breast cancer is the most common cancer worldwide. Hypoxia and lactate metabolism are hallmarks of cancer. This study aimed to construct a novel hypoxia- and lactate metabolism-related gene signature to predict the survival, immune microenvironment, and treatment response of breast cance...

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Detalles Bibliográficos
Autores principales: Li, Jia, Qiao, Hao, Wu, Fei, Sun, Shiyu, Feng, Cong, Li, Chaofan, Yan, Wanjun, Lv, Wei, Wu, Huizi, Liu, Mengjie, Chen, Xi, Liu, Xuan, Wang, Weiwei, Cai, Yifan, Zhang, Yu, Zhou, Zhangjian, Zhang, Yinbin, Zhang, Shuqun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9585224/
https://www.ncbi.nlm.nih.gov/pubmed/36275774
http://dx.doi.org/10.3389/fimmu.2022.998140