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Lipids for CD8(+) TILs: Beneficial or harmful?

Lipids and lipid metabolism play crucial roles in regulating T cell function and are tightly related to the establishment of immune memory. It is reported that tumor-infiltrating CD8(+)T lymphocytes (CD8(+)TILs) burn fats to restore their impaired effector function due to the lack of glucose. Conver...

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Detalles Bibliográficos
Autores principales: Wu, Duojiao, Chen, Yuwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9585227/
https://www.ncbi.nlm.nih.gov/pubmed/36275711
http://dx.doi.org/10.3389/fimmu.2022.1020422