Ginsenoside Rc, as an FXR activator, alleviates acetaminophen-induced hepatotoxicity via relieving inflammation and oxidative stress

Acetaminophen (APAP) intake leads to excessive NAPQI deposition, stimulating inflammatory and oxidative stress and causing fatal liver injury. However, the detailed molecular mechanism involved is unknown, and effective therapeutic approaches remain insufficient. In this study, we discovered that tr...

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Detalles Bibliográficos
Autores principales: Zhong, Yadi, Chen, Yingjian, Pan, Zhisen, Tang, Kaijia, Zhong, Guangcheng, Guo, Jingyi, Cui, Tianqi, Li, Tianyao, Duan, Siwei, Yang, Xiaoying, Gao, Yong, Wang, Qi, Zhang, Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9585238/
https://www.ncbi.nlm.nih.gov/pubmed/36278209
http://dx.doi.org/10.3389/fphar.2022.1027731

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9585238/
https://www.ncbi.nlm.nih.gov/pubmed/36278209
http://dx.doi.org/10.3389/fphar.2022.1027731

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