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Distinct mRNA and protein interactomes highlight functional differentiation of major eIF4F-like complexes from Trypanosoma brucei

Gene expression in pathogenic protozoans of the family Trypanosomatidae has several novel features, including multiple eIF4F-like complexes involved in protein synthesis. The eukaryotic eIF4F complex, formed mainly by eIF4E and eIF4G subunits, is responsible for the canonical selection of mRNAs requ...

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Detalles Bibliográficos
Autores principales: Bezerra, Maria J. R., Moura, Danielle M. N., Freire, Eden R., Holetz, Fabiola B., Reis, Christian R. S., Monteiro, Tallyta T. S., Pinto, Adriana R. S., Zhang, Ning, Rezende, Antonio M., Pereira-Neves, Antonio, Figueiredo, Regina C. B. Q., Clayton, Christine, Field, Mark C., Carrington, Mark, de Melo Neto, Osvaldo P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9585242/
https://www.ncbi.nlm.nih.gov/pubmed/36275617
http://dx.doi.org/10.3389/fmolb.2022.971811