Polydatin attenuates tubulointerstitial fibrosis in diabetic kidney disease by inhibiting YAP expression and nuclear translocation

The activation of Yes-associated protein (YAP) pathway is mutually causal with the increase of extracellular matrix (ECM) stiffness. Polydatin (PD) has been proved to have anti-fibrosis effect in diabetic kidney disease (DKD), but it is still a mystery whether PD participates in YAP-related mechano-...

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Detalles Bibliográficos
Autores principales: He, Manlin, Feng, Lan, Chen, Yang, Gao, Bin, Du, Yiwei, Zhou, Lu, Li, Fei, Liu, Hongbao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9585250/
https://www.ncbi.nlm.nih.gov/pubmed/36277194
http://dx.doi.org/10.3389/fphys.2022.927794

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9585250/
https://www.ncbi.nlm.nih.gov/pubmed/36277194
http://dx.doi.org/10.3389/fphys.2022.927794

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