B7-H3-targeting Fc-optimized antibody for induction of NK cell reactivity against sarcoma

Natural killer (NK) cells largely contribute to antibody-dependent cellular cytotoxicity (ADCC), a central factor for success of monoclonal antibodies (mAbs) treatment of cancer. The B7 family member B7-H3 (CD276) recently receives intense interest as a novel promising target antigen for immunothera...

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Detalles Bibliográficos
Autores principales: Hagelstein, Ilona, Engel, Monika, Hinterleitner, Clemens, Manz, Timo, Märklin, Melanie, Jung, Gundram, Salih, Helmut R., Zekri, Latifa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9585277/
https://www.ncbi.nlm.nih.gov/pubmed/36275693
http://dx.doi.org/10.3389/fimmu.2022.1002898

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9585277/
https://www.ncbi.nlm.nih.gov/pubmed/36275693
http://dx.doi.org/10.3389/fimmu.2022.1002898

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