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cAMP-specific phosphodiesterase 8A and 8B isoforms are differentially expressed in human testis and Leydig cell tumor

Cyclic adenosine monophosphate/Protein kinase A (cAMP/PKA) signaling pathway is the master regulator of endocrine tissue function. The level, compartmentalization and amplitude of cAMP response are finely regulated by phosphodiesterases (PDEs). PDE8 is responsible of cAMP hydrolysis and its expressi...

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Detalles Bibliográficos
Autores principales: Campolo, Federica, Capponi, Chiara, Tarsitano, Maria Grazia, Tenuta, Marta, Pozza, Carlotta, Gianfrilli, Daniele, Magliocca, Fabio, Venneri, Mary A., Vicini, Elena, Lenzi, Andrea, Isidori, Andrea M., Barbagallo, Federica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9585345/
https://www.ncbi.nlm.nih.gov/pubmed/36277728
http://dx.doi.org/10.3389/fendo.2022.1010924