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Concise two-step chemical synthesis of molnupiravir

A concise synthesis of molnupiravir in a one-pot two-step approach starting from uridine is described. Formally, herein, two sets of one-pot two-reaction steps introducing simplicity for purifications and using chemically available reagents are presented. In this context, molnupiravir was obtained i...

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Detalles Bibliográficos
Autores principales: Pereira, Vinícius R. D., Bezerra, Marco A. M., Gomez, Mauro R. B. P., Martins, Guilherme M., da Silva, Adilson D., de Oliveira, Kleber T., de Souza, Rodrigo O. M. A., Amarante, Giovanni W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9585438/
https://www.ncbi.nlm.nih.gov/pubmed/36329948
http://dx.doi.org/10.1039/d2ra05064a