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In Vitro Demonstration of Human Lipoyl Synthase Catalytic Activity in the Presence of NFU1

[Image: see text] Lipoyl synthase (LS) catalyzes the last step in the biosynthesis of the lipoyl cofactor, which is the attachment of sulfur atoms at C6 and C8 of an n-octanoyllysyl side chain of a lipoyl carrier protein (LCP). The protein is a member of the radical S-adenosylmethionine (SAM) superf...

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Detalles Bibliográficos
Autores principales: Warui, Douglas M., Sil, Debangsu, Lee, Kyung-Hoon, Neti, Syam Sundar, Esakova, Olga A., Knox, Hayley L., Krebs, Carsten, Booker, Squire J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9585516/
https://www.ncbi.nlm.nih.gov/pubmed/36281303
http://dx.doi.org/10.1021/acsbiomedchemau.2c00020