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Validation and application of a high-fidelity, computational model of acute respiratory distress syndrome to the examination of the indices of oxygenation at constant lung-state

BACKGROUND: Calculated venous admixture (Qs/Qt) is considered the best index of oxygenation; surrogates have been developed (Pa(o(2))/Fi(o(2)), respiratory index, and arterioalveolar Po(2) difference), but these vary with Fi(o(2)), falsely indicating a change in lung-state. Using a novel model, we a...

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Detalles Bibliográficos
Autores principales: McCahon, R.A., Columb, M.O., Mahajan, R.P., Hardman, J.G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: British Journal of Anaesthesia. Published by Elsevier Ltd. 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9585629/
https://www.ncbi.nlm.nih.gov/pubmed/18567677
http://dx.doi.org/10.1093/bja/aen181