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Maternal blood pressure associates with placental DNA methylation both directly and through alterations in cell-type composition

BACKGROUND: Maternal blood pressure levels reflect cardiovascular adaptation to pregnancy and proper maternal-fetal exchanges through the placenta and are very sensitive to numerous environmental stressors. Maternal hypertension during pregnancy has been associated with impaired placental functions...

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Detalles Bibliográficos
Autores principales: Broséus, Lucile, Vaiman, Daniel, Tost, Jörg, Martin, Camino Ruano San, Jacobi, Milan, Schwartz, Joel D., Béranger, Rémi, Slama, Rémy, Heude, Barbara, Lepeule, Johanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9585724/
https://www.ncbi.nlm.nih.gov/pubmed/36266660
http://dx.doi.org/10.1186/s12916-022-02610-y