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Combined enhancement of the propionyl-CoA metabolic pathway for efficient androstenedione production in Mycolicibacterium neoaurum

BACKGROUND: The production of androstenedione (AD) from phytosterols by Mycolicibacterium neoaurum is a multi-step biotransformation process, which requires degradation of sterol side chains, accompanied by the production of propionyl-CoA. However, the transient production of large amounts of propio...

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Detalles Bibliográficos
Autores principales: Su, Zhenhua, Zhang, Zhenjian, Yu, Jian, Yuan, Congcong, Shen, Yanbing, Wang, Jianxin, Su, Liqiu, Wang, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9585753/
https://www.ncbi.nlm.nih.gov/pubmed/36266684
http://dx.doi.org/10.1186/s12934-022-01942-x