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rs2013278 in the multiple immunological-trait susceptibility locus CD28 regulates the production of non-functional splicing isoforms

BACKGROUND: Ligation of CD28 with ligands such as CD80 or CD86 provides a critical second signal alongside antigen presentation by class II major histocompatibility complex expressed on antigen-presenting cells through the T cell antigen receptor for naïve T cell activation. A number of studies sugg...

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Detalles Bibliográficos
Autores principales: Hitomi, Yuki, Aiba, Yoshihiro, Ueno, Kazuko, Nishida, Nao, Kawai, Yosuke, Kawashima, Minae, Tsuiji, Makoto, Iwabuchi, Chisato, Takada, Sanami, Miyake, Noriko, Nagasaki, Masao, Tokunaga, Katsushi, Nakamura, Minoru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9585755/
https://www.ncbi.nlm.nih.gov/pubmed/36271469
http://dx.doi.org/10.1186/s40246-022-00419-7