Metabolic Maturation Increases Susceptibility to Hypoxia-induced Damage in Human iPSC-derived Cardiomyocytes

The development of new cardioprotective approaches using in vivo models of ischemic heart disease remains challenging as differences in cardiac physiology, phenotype, and disease progression between humans and animals influence model validity and prognostic value. Furthermore, economical and ethical...

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Detalles Bibliográficos
Autores principales: Peters, Marijn C, Maas, Renee G C, van Adrichem, Iris, Doevendans, Pieter A M, Mercola, Mark, Šarić, Tomo, Buikema, Jan W, van Mil, Alain, Chamuleau, Steven A J, Sluijter, Joost P G, Hnatiuk, Anna P, Neef, Klaus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Cell-Based Drug Development, Screening, and Toxicology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9585948/
https://www.ncbi.nlm.nih.gov/pubmed/36018047
http://dx.doi.org/10.1093/stcltm/szac061

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9585948/
https://www.ncbi.nlm.nih.gov/pubmed/36018047
http://dx.doi.org/10.1093/stcltm/szac061

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