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IQGAP3 in clear cell renal cell carcinoma contributes to drug resistance and genome stability
BACKGROUND: Clear cell renal clear cell carcinoma (ccRCC) is resistant to most chemotherapeutic drugs and the molecular mechanisms have not been fully revealed. Genomic instability and the abnormal activation of bypass DNA repair pathway is the potential cause of tumor resistance to radiotherapy and...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
PeerJ Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9586079/ https://www.ncbi.nlm.nih.gov/pubmed/36275458 http://dx.doi.org/10.7717/peerj.14201 |