Cargando…

IQGAP3 in clear cell renal cell carcinoma contributes to drug resistance and genome stability

BACKGROUND: Clear cell renal clear cell carcinoma (ccRCC) is resistant to most chemotherapeutic drugs and the molecular mechanisms have not been fully revealed. Genomic instability and the abnormal activation of bypass DNA repair pathway is the potential cause of tumor resistance to radiotherapy and...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Wen, Wang, Zhifeng, Wang, Hanlin, Zhang, Jian, Wang, Xiaobin, Xing, Shaojun, Chen, Si
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	PeerJ Inc. 2022
Materias:	Bioinformatics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9586079/ https://www.ncbi.nlm.nih.gov/pubmed/36275458 http://dx.doi.org/10.7717/peerj.14201

Ejemplares similares

Key genes associated with prognosis and metastasis of clear cell renal cell carcinoma
por: Zhong, Tingting, et al.
Publicado: (2022)

Prognostic significance and tumor-immune infiltration of mTOR in clear cell renal cell carcinoma
por: Li, Na, et al.
Publicado: (2021)

IQGAP3 May Serve as a Promising Biomarker in Clear Cell Renal Cell Carcinoma
por: Meng, Quan, et al.
Publicado: (2021)

AURKB: a promising biomarker in clear cell renal cell carcinoma
por: Wan, Bangbei, et al.
Publicado: (2019)

Bioinformatic analysis identifies potentially key differentially expressed genes in oncogenesis and progression of clear cell renal cell carcinoma
por: Zhang, Haiping, et al.
Publicado: (2019)

Microenvironment-related gene TNFSF13B predicts poor prognosis in kidney renal clear cell carcinoma
por: Jiang, Mingzhe, et al.
Publicado: (2020)

A novel gene signature related to oxidative stress predicts the prognosis in clear cell renal cell carcinoma
por: Ma, Sheng, et al.
Publicado: (2023)

Comprehensive analysis of a new prognosis signature based on histone deacetylases in clear cell renal cell carcinoma
por: Cheng, Fajuan, et al.
Publicado: (2021)

NFIB promotes the migration and progression of kidney renal clear cell carcinoma by regulating PINK1 transcription
por: Wang, Ninghua, et al.
Publicado: (2021)

Increased expression of RUNX1 in clear cell renal cell carcinoma predicts poor prognosis
por: Fu, Yang, et al.
Publicado: (2019)

Reduced GRAMD1C expression correlates to poor prognosis and immune infiltrates in kidney renal clear cell carcinoma
por: Hao, Haiyan, et al.
Publicado: (2019)

Identification of a glycolysis-related lncRNA prognostic signature for clear cell renal cell carcinoma
por: Ma, Wei, et al.
Publicado: (2021)

Prognostic significance of PI3K/AKT/ mTOR signaling pathway members in clear cell renal cell carcinoma
por: Fan, Demin, et al.
Publicado: (2020)

Prognostic value of sirtuin family members and experimental verification identify SIRT5 as diagnostic biomarkers in clear cell renal cell carcinoma
por: Peng, Lu-Shan, et al.
Publicado: (2023)

Downregulation of PPA2 expression correlates with poor prognosis of kidney renal clear cell carcinoma
por: Zhu, Wenbiao, et al.
Publicado: (2021)

Identification of DNA methylation patterns and biomarkers for clear-cell renal cell carcinoma by multi-omics data analysis
por: Liu, Pengfei, et al.
Publicado: (2020)

Profiles of overall survival-related gene expression-based risk signature and their prognostic implications in clear cell renal cell carcinoma
por: He, Zihao, et al.
Publicado: (2020)

A 14 immune-related gene signature predicts clinical outcomes of kidney renal clear cell carcinoma
por: Zou, Yong, et al.
Publicado: (2020)

A microRNA‐clinical prognosis model to predict the overall survival for kidney renal clear cell carcinoma
por: Zhan, Yating, et al.
Publicado: (2021)

Traditional Chinese medicine Bu-Shen-Jian-Pi-Fang attenuates glycolysis and immune escape in clear cell renal cell carcinoma: results based on network pharmacology
por: Zheng, Jinzhou, et al.
Publicado: (2021)

Prediction and analysis of novel key genes ITGAX, LAPTM5, SERPINE1 in clear cell renal cell carcinoma through bioinformatics analysis
por: Sui, Yingli, et al.
Publicado: (2021)

Long non-coding RNA LINC01234 regulates proliferation, migration and invasion via HIF-2α pathways in clear cell renal cell carcinoma cells
por: Yang, Feilong, et al.
Publicado: (2020)

Novel prognostic prediction model constructed through machine learning on the basis of methylation-driven genes in kidney renal clear cell carcinoma
por: Tang, Weihao, et al.
Publicado: (2020)

Identification of a three-m6A related gene risk score model as a potential prognostic biomarker in clear cell renal cell carcinoma
por: Zhao, Yiqiao, et al.
Publicado: (2020)

Key sunitinib‐related biomarkers for renal cell carcinoma
por: Peng, Yun, et al.
Publicado: (2021)

Identification of the miRNA-mRNA regulatory pathways and a miR-21-5p based nomogram model in clear cell renal cell carcinoma
por: Zhao, Yiqiao, et al.
Publicado: (2020)

Identification and validation of a ferroptosis-related lncRNA signature to robustly predict the prognosis, immune microenvironment, and immunotherapy efficiency in patients with clear cell renal cell carcinoma
por: Ju, Lincheng, et al.
Publicado: (2022)

Quantitative ubiquitylomics reveals the ubiquitination regulation landscape in oral adenoid cystic carcinoma
por: Li, Wen, et al.
Publicado: (2021)

Next-generation sequencing shows the genomic features of ovarian clear cell cancer and compares the genetic architectures of high-grade serous ovarian cancer and clear cell carcinoma in ovarian and endometrial tissues
por: Gan, Meifu, et al.
Publicado: (2023)

Integrated bioinformatics analysis of the NEDD4 family reveals a prognostic value of NEDD4L in clear-cell renal cell cancer
por: Zhao, Hui, et al.
Publicado: (2021)

FTH1 indicates poor prognosis and promotes metastasis in head and neck squamous cell carcinoma
por: Liao, Qingyun, et al.
Publicado: (2023)

Integrated analysis of differentially expressed profiles and construction of a competing endogenous long non-coding RNA network in renal cell carcinoma
por: Xing, Qianwei, et al.
Publicado: (2018)

Identification of PSMD7 as a prognostic factor correlated with immune infiltration in head and neck squamous cell carcinoma
por: Zhang, Si, et al.
Publicado: (2021)

Revealing potential lipid biomarkers in clear cell renal cell carcinoma using targeted quantitative lipidomics
por: Li, Wen, et al.
Publicado: (2021)

Circular RNA expression profile of lung squamous cell carcinoma: identification of potential biomarkers and therapeutic targets
por: Wang, Yawei, et al.
Publicado: (2020)

High mutations in fatty acid metabolism contribute to a better prognosis of small‐cell lung cancer patients treated with chemotherapy
por: Lyu, Qiong, et al.
Publicado: (2021)

Exploration of immune-related genes in high and low tumor mutation burden groups of chromophobe renal cell carcinoma
por: Li, Lei, et al.
Publicado: (2020)

Immune cell landscape analysis reveals prognostic immune cells and its potential mechanism in squamous cell lung carcinoma
por: Wang, Yongyong, et al.
Publicado: (2020)

IQGAP1 and IQGAP2 are Reciprocally Altered in Hepatocellular Carcinoma
por: White, Colin D, et al.
Publicado: (2010)

The roles of ferroptosis regulatory gene SLC7A11 in renal cell carcinoma: A multi‐omics study
por: Xu, Fangshi, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_e3u7o5n4llqp2c7qbhfn28r6d2