Inhibition of FOXP3 by stapled alpha-helical peptides dampens regulatory T cell function

Despite continuing advances in the development of novel cellular-, antibody-, and chemotherapeutic-based strategies to enhance immune reactivity, the presence of regulatory T cells (Treg cells) remains a complicating factor for their clinical efficacy. To overcome dosing limitations and off-target e...

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Detalles Bibliográficos
Autores principales: Hawley, Katrina M., Eclov, Rachel J., Schnorenberg, Mathew R., Tian, Yu, Shah, Rhea N., Thomas-Toth, Anika T., Fefferman, Marie, Bird, Gregory H., Walensky, Loren D., Tirrell, Matthew V., LaBelle, James L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9586281/
https://www.ncbi.nlm.nih.gov/pubmed/36227917
http://dx.doi.org/10.1073/pnas.2209044119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9586281/
https://www.ncbi.nlm.nih.gov/pubmed/36227917
http://dx.doi.org/10.1073/pnas.2209044119

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