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Inhibition of FOXP3 by stapled alpha-helical peptides dampens regulatory T cell function
Despite continuing advances in the development of novel cellular-, antibody-, and chemotherapeutic-based strategies to enhance immune reactivity, the presence of regulatory T cells (Treg cells) remains a complicating factor for their clinical efficacy. To overcome dosing limitations and off-target e...
| Autores principales: | , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
National Academy of Sciences
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9586281/ https://www.ncbi.nlm.nih.gov/pubmed/36227917 http://dx.doi.org/10.1073/pnas.2209044119 |