Cargando…

Tetraspanin-5–mediated MHC class I clustering is required for optimal CD8 T cell activation

MHC molecules are not randomly distributed on the plasma membrane but instead are present in discrete nanoclusters. The mechanisms that control formation of MHC I nanoclusters and the importance of such structures are incompletely understood. Here, we report a molecular association between tetraspan...

Descripción completa

Detalles Bibliográficos
Autores principales: Colbert, Jeff D., Cruz, Freidrich M., Baer, Christina E., Rock, Kenneth L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9586303/
https://www.ncbi.nlm.nih.gov/pubmed/36215490
http://dx.doi.org/10.1073/pnas.2122188119