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Tetraspanin-5–mediated MHC class I clustering is required for optimal CD8 T cell activation
MHC molecules are not randomly distributed on the plasma membrane but instead are present in discrete nanoclusters. The mechanisms that control formation of MHC I nanoclusters and the importance of such structures are incompletely understood. Here, we report a molecular association between tetraspan...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
National Academy of Sciences
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9586303/ https://www.ncbi.nlm.nih.gov/pubmed/36215490 http://dx.doi.org/10.1073/pnas.2122188119 |