Substitutions near the HA receptor binding site explain the origin and major antigenic change of the B/Victoria and B/Yamagata lineages

Influenza B virus primarily infects humans, causing seasonal epidemics globally. Two antigenic variants—Victoria-like and Yamagata-like—were detected in the 1980s, of which the molecular basis of emergence is still incompletely understood. Here, the antigenic properties of a unique collection of his...

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Detalles Bibliográficos
Autores principales: Rosu, Miruna E., Lexmond, Pascal, Bestebroer, Theo M., Hauser, Blake M., Smith, Derek J., Herfst, Sander, Fouchier, Ron A. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9586307/
https://www.ncbi.nlm.nih.gov/pubmed/36215486
http://dx.doi.org/10.1073/pnas.2211616119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9586307/
https://www.ncbi.nlm.nih.gov/pubmed/36215486
http://dx.doi.org/10.1073/pnas.2211616119

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