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Direct observation of stepping rotation of V-ATPase reveals rigid component in coupling between V(o) and V(1) motors

V-ATPases are rotary motor proteins that convert the chemical energy of ATP into the electrochemical potential of ions across cell membranes. V-ATPases consist of two rotary motors, V(o) and V(1), and Enterococcus hirae V-ATPase (EhV(o)V(1)) actively transports Na(+) in V(o) (EhV(o)) by using torque...

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Detalles Bibliográficos
Autores principales: Otomo, Akihiro, Iida, Tatsuya, Okuni, Yasuko, Ueno, Hiroshi, Murata, Takeshi, Iino, Ryota
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9586324/
https://www.ncbi.nlm.nih.gov/pubmed/36215468
http://dx.doi.org/10.1073/pnas.2210204119