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Aqueous microdroplets enable abiotic synthesis and chain extension of unique peptide isomers from free amino acids
Amide bond formation, the essential condensation reaction underlying peptide synthesis, is hindered in aqueous systems by the thermodynamic constraints associated with dehydration. This represents a key difficulty for the widely held view that prebiotic chemical evolution leading to the formation of...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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National Academy of Sciences
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9586328/ https://www.ncbi.nlm.nih.gov/pubmed/36191178 http://dx.doi.org/10.1073/pnas.2212642119 |