LYL1 facilitates AETFC assembly and gene activation by recruiting CARM1 in t(8;21) AML

Transcription factors (TFs) play critical roles in hematopoiesis, and their aberrant expression can lead to various types of leukemia. The t(8;21) leukemogenic fusion protein AML1–ETO (AE) is the most common fusion protein in acute myeloid leukemia and can enhance hematopoietic stem cell renewal whi...

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Detalles Bibliográficos
Autores principales: Chen, Qian, Cevher, Murat A., Jiang, Qi, Wang, Saisai, Sun, Xiaojian, Roeder, Robert G., Chen, Mo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9586329/
https://www.ncbi.nlm.nih.gov/pubmed/36215477
http://dx.doi.org/10.1073/pnas.2213718119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9586329/
https://www.ncbi.nlm.nih.gov/pubmed/36215477
http://dx.doi.org/10.1073/pnas.2213718119

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