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LYL1 facilitates AETFC assembly and gene activation by recruiting CARM1 in t(8;21) AML

Transcription factors (TFs) play critical roles in hematopoiesis, and their aberrant expression can lead to various types of leukemia. The t(8;21) leukemogenic fusion protein AML1–ETO (AE) is the most common fusion protein in acute myeloid leukemia and can enhance hematopoietic stem cell renewal whi...

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Detalles Bibliográficos
Autores principales:	Chen, Qian, Cevher, Murat A., Jiang, Qi, Wang, Saisai, Sun, Xiaojian, Roeder, Robert G., Chen, Mo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	National Academy of Sciences 2022
Materias:	Biological Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9586329/ https://www.ncbi.nlm.nih.gov/pubmed/36215477 http://dx.doi.org/10.1073/pnas.2213718119

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