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Identification of immune-related mechanisms of cetuximab induced skin toxicity in colorectal cancer patients

Skin rash is a well-known predictive marker of the response to cetuximab (Cmab) in metastatic colorectal cancer (mCRC). However, the mechanism of skin rash development is not well understood. Following exposure to EGFR-targeted therapies, changes in IL-8 levels have been reported. The aim of this st...

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Detalles Bibliográficos
Autores principales: Park, Jin Hyun, Kim, Mi Young, Choi, In Sil, Kim, Ji-Won, Kim, Jin Won, Lee, Keun-Wook, Kim, Jin-Soo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9586384/
https://www.ncbi.nlm.nih.gov/pubmed/36269747
http://dx.doi.org/10.1371/journal.pone.0276497