Exocyst inactivation in urothelial cells disrupts autophagy and activates non-canonical NF-κB signaling

Ureter obstruction is a highly prevalent event during embryonic development and is a major cause of pediatric kidney disease. We have previously reported that ureteric bud-specific ablation of the gene expressing the exocyst subunit EXOC5 in late murine gestation results in failure of urothelial str...

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Detalles Bibliográficos
Autores principales: Ortega, Michael A., Villiger, Ross K., Harrison-Chau, Malia, Lieu, Suzanna, Tamashiro, Kadee-Kalia, Lee, Amanda J., Fujimoto, Brent A., Patwardhan, Geetika Y., Kepler, Joshua, Fogelgren, Ben
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9586569/
https://www.ncbi.nlm.nih.gov/pubmed/36004645
http://dx.doi.org/10.1242/dmm.049785

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9586569/
https://www.ncbi.nlm.nih.gov/pubmed/36004645
http://dx.doi.org/10.1242/dmm.049785

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