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A clinically relevant model of acute respiratory distress syndrome in human-size swine

Despite over 30 years of intensive research for targeted therapies, treatment of acute respiratory distress syndrome (ARDS) remains supportive in nature. With mortality upwards of 30%, a high-fidelity pre-clinical model of ARDS, on which to test novel therapeutics, is urgently needed. We used the Yo...

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Detalles Bibliográficos
Autores principales: Kaslow, Sarah R., Reimer, Jonathan A., Pinezich, Meghan R., Hudock, Maria R., Chen, Panpan, Morris, Mariya G., Kain, Mandy L., Leb, Jay S., Ruzal-Shapiro, Carrie B., Marboe, Charles C., Bacchetta, Matthew, Dorrello, N. Valerio, Vunjak-Novakovic, Gordana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9586570/
https://www.ncbi.nlm.nih.gov/pubmed/35976034
http://dx.doi.org/10.1242/dmm.049603