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β-catenin ISGylation promotes lipid deposition and apoptosis in ethanol-stimulated liver injury models

BACKGROUND: The restoration of the Wnt/β-catenin pathway to alleviate alcoholic fatty liver disease (AFLD) progression is under study as a new strategy for alcoholic liver disease (ALD) treatment. Recent studies have indicated that interferon-stimulated gene 15 (ISG15) can covalently bind to β-caten...

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Detalles Bibliográficos
Autores principales: Ding, Qi, Zhang, Guodong, Wang, Yang, Xu, Lei, Wu, Meifei, Zhou, Yiwen, Xu, Tao, Meng, Xiaoming, Huang, Cheng, Zhang, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9586657/
https://www.ncbi.nlm.nih.gov/pubmed/36259544
http://dx.doi.org/10.1080/13510002.2022.2109360