Cargando…

β-catenin ISGylation promotes lipid deposition and apoptosis in ethanol-stimulated liver injury models

BACKGROUND: The restoration of the Wnt/β-catenin pathway to alleviate alcoholic fatty liver disease (AFLD) progression is under study as a new strategy for alcoholic liver disease (ALD) treatment. Recent studies have indicated that interferon-stimulated gene 15 (ISG15) can covalently bind to β-caten...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ding, Qi, Zhang, Guodong, Wang, Yang, Xu, Lei, Wu, Meifei, Zhou, Yiwen, Xu, Tao, Meng, Xiaoming, Huang, Cheng, Zhang, Lei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9586657/ https://www.ncbi.nlm.nih.gov/pubmed/36259544 http://dx.doi.org/10.1080/13510002.2022.2109360

Ejemplares similares

90K Glycoprotein Promotes Degradation of Mutant β-Catenin Lacking the ISGylation or Phosphorylation Sites in the N-terminus()()
por: Park, So-Yeon, et al.
Publicado: (2016)

CYP1B1 Activates Wnt/β-Catenin Signaling through Suppression of Herc5-Mediated ISGylation for Protein Degradation on β-Catenin in HeLa Cells
por: Park, Young-Shin, et al.
Publicado: (2017)

The Functional Roles of ISG15/ISGylation in Cancer
por: Yuan, Yin, et al.
Publicado: (2023)

ISG15 and ISGylation in Human Diseases
por: Mirzalieva, Oygul, et al.
Publicado: (2022)

ISGylation-independent protection of cell growth by USP18 following interferon stimulation
por: Clancy, Anne, et al.
Publicado: (2023)

Proteomics Mapping of the ISGylation Landscape in Innate Immunity
por: Thery, Fabien, et al.
Publicado: (2021)

ISG15 suppresses ovulation and female fertility by ISGylating ADAMTS1
por: Chen, Yaru, et al.
Publicado: (2023)

ISGylation orchestrates the degradation flux of cellular cargo toward lysosome
por: Huang, Min-Yi, et al.
Publicado: (2021)

Induced TRIM21 ISGylation by IFN-β enhances p62 ubiquitination to prevent its autophagosome targeting
por: Jin, Jie, et al.
Publicado: (2021)

YAP ISGylation increases its stability and promotes its positive regulation on PPP by stimulating 6PGL transcription
por: Xue, Xiangfei, et al.
Publicado: (2022)

Oncogene-mediated regulation of p53 ISGylation and functions
por: Huang, Yi-Fu, et al.
Publicado: (2014)

Targeting the Ubiquitylation and ISGylation Machinery for the Treatment of COVID-19
por: Vere, George, et al.
Publicado: (2022)

ISG15 and ISGylation modulates cancer stem cell-like characteristics in promoting tumor growth of anaplastic thyroid carcinoma
por: Xu, Tong, et al.
Publicado: (2023)

Posttranslational ISGylation of NLRP3 by HERC enzymes facilitates inflammasome activation in models of inflammation
por: Qin, Ying, et al.
Publicado: (2023)

ISGylation in Innate Antiviral Immunity and Pathogen Defense Responses: A Review
por: Zhang, Mengdi, et al.
Publicado: (2021)

Bmal1 Regulates Macrophage Polarize Through Glycolytic Pathway in Alcoholic Liver Disease
por: Zhou, Yiwen, et al.
Publicado: (2021)

Parkin deficiency prevents chronic ethanol-induced hepatic lipid accumulation through β-catenin accumulation
por: Lee, Dong Hun, et al.
Publicado: (2019)

Consecutive Inhibition of ISG15 Expression and ISGylation by Cytomegalovirus Regulators
por: Kim, Ye Ji, et al.
Publicado: (2016)

Upregulation of Enzymes involved in ISGylation and Ubiquitination in patients with hepatocellular carcinoma
por: Tong, Hoang Van, et al.
Publicado: (2020)

Protein ISGylation: a posttranslational modification with implications for malignant neoplasms
por: Tecalco-Cruz, Angeles C., et al.
Publicado: (2023)

HyperISGylation of Old World Monkey ISG15 in Human Cells
por: Pattyn, Els, et al.
Publicado: (2008)

ISGylation controls exosome secretion by promoting lysosomal degradation of MVB proteins
por: Villarroya-Beltri, Carolina, et al.
Publicado: (2016)

Inflammatory osteolysis is regulated by site-specific ISGylation of the scaffold protein NEMO
por: Adapala, Naga Suresh, et al.
Publicado: (2020)

HERC5 and the ISGylation Pathway: Critical Modulators of the Antiviral Immune Response
por: Mathieu, Nicholas A., et al.
Publicado: (2021)

ISGylation of EMD promotes its interaction with PDHA to inhibit aerobic oxidation in lung adenocarcinoma
por: Zhang, Congcong, et al.
Publicado: (2022)

Rev-erbα exacerbates hepatic steatosis in alcoholic liver diseases through regulating autophagy
por: Liu, Qingxue, et al.
Publicado: (2021)

RBM5 inhibits tumorigenesis of gliomas through inhibition of Wnt/β-catenin signaling and induction of apoptosis
por: Jiang, Yuanpei, et al.
Publicado: (2017)

Ring finger protein 213 assembles into a sensor for ISGylated proteins with antimicrobial activity
por: Thery, Fabien, et al.
Publicado: (2021)

Modulation of the Host Interferon Response and ISGylation Pathway by B. pertussis Filamentous Hemagglutinin
por: Dieterich, Christine, et al.
Publicado: (2011)

Decoupling deISGylating and deubiquitinating activities of the MERS virus papain-like protease
por: Clasman, Jozlyn R., et al.
Publicado: (2020)

ISGylation is induced in neurons by demyelination driving ISG15-dependent microglial activation
por: Clarkson, Benjamin D. S., et al.
Publicado: (2022)

STAT3 paradoxically stimulates β-catenin expression but inhibits β-catenin function
por: Ibrahem, Salih, et al.
Publicado: (2014)

FOXO3a is stabilized by USP18-mediated de-ISGylation and inhibits TGF-β1-induced fibronectin expression
por: Wang, Ban, et al.
Publicado: (2020)

Zoledronate promotes ECM degradation and apoptosis via Wnt/β-catenin
por: Xiao, Jialing, et al.
Publicado: (2022)

H19 knockdown suppresses proliferation and induces apoptosis by regulating miR-148b/WNT/β-catenin in ox-LDL -stimulated vascular smooth muscle cells
por: Zhang, Lei, et al.
Publicado: (2018)

Nidovirus papain-like proteases: Multifunctional enzymes with protease, deubiquitinating and deISGylating activities
por: Mielech, Anna M., et al.
Publicado: (2014)

MERS-CoV papain-like protease has deISGylating and deubiquitinating activities
por: Mielech, Anna M., et al.
Publicado: (2014)

ISG15 and ISGylation is required for pancreatic cancer stem cell mitophagy and metabolic plasticity
por: Alcalá, Sonia, et al.
Publicado: (2020)

Deletion of the deISGylating enzyme USP18 enhances tumour cell antigenicity and radiosensitivity
por: Pinto-Fernandez, Adan, et al.
Publicado: (2020)

ISGylation drives basal breast tumour progression by promoting EGFR recycling and Akt signalling
por: Bolado-Carrancio, Alfonso, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_9hv68pcbaaog3tej0kt99a091l