Pharmacoepigenetics of hypertension: genome-wide methylation analysis of responsiveness to four classes of antihypertensive drugs using a double-blind crossover study design

Essential hypertension remains the leading risk factor of global disease burden, but its treatment goals are often not met. We investigated whether DNA methylation is associated with antihypertensive responses to a diuretic, a beta-blocker, a calcium channel blocker or an angiotensin receptor antago...

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Detalles Bibliográficos
Autores principales: Nuotio, Marja-Liisa, Sánez Tähtisalo, Heini, Lahtinen, Alexandra, Donner, Kati, Fyhrquist, Frej, Perola, Markus, Kontula, Kimmo K, Hiltunen, Timo P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9586691/
https://www.ncbi.nlm.nih.gov/pubmed/35213289
http://dx.doi.org/10.1080/15592294.2022.2038418

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9586691/
https://www.ncbi.nlm.nih.gov/pubmed/35213289
http://dx.doi.org/10.1080/15592294.2022.2038418

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