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Simvastatin Inhibits Endometrial Cancer Malignant Behaviors by Suppressing RAS/Mitogen-Activated Protein Kinase (MAPK) Pathway-Mediated Reactive Oxygen Species (ROS) and Ferroptosis

This paper was designed to explore the function of simvastatin as a chemotherapeutic drug on the endometrial cancer (EC) cell proliferation, invasion, and ferroptosis. Firstly, a number of in vitro experiments were conducted to determine the impact of different treatments of simvastatin on the Ishik...

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Detalles Bibliográficos
Autores principales: Zhou, Dan, Wu, Qiuhua, Qiu, Huajuan, Li, Mi, Ji, Yanqin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9586725/
https://www.ncbi.nlm.nih.gov/pubmed/36276874
http://dx.doi.org/10.1155/2022/6177477