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Multimodal integration of radiology, pathology and genomics for prediction of response to PD-(L)1 blockade in patients with non-small cell lung cancer

Immunotherapy is used to treat almost all patients with advanced non-small cell lung cancer (NSCLC); however, identifying robust predictive biomarkers remains challenging. Here we show the predictive capacity of integrating medical imaging, histopathologic and genomic features to predict immunothera...

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Detalles Bibliográficos
Autores principales: Vanguri, Rami S., Luo, Jia, Aukerman, Andrew T., Egger, Jacklynn V., Fong, Christopher J., Horvat, Natally, Pagano, Andrew, Araujo-Filho, Jose de Arimateia Batista, Geneslaw, Luke, Rizvi, Hira, Sosa, Ramon, Boehm, Kevin M., Yang, Soo-Ryum, Bodd, Francis M., Ventura, Katia, Hollmann, Travis J., Ginsberg, Michelle S., Gao, Jianjiong, Hellmann, Matthew D., Sauter, Jennifer L., Shah, Sohrab P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9586871/
https://www.ncbi.nlm.nih.gov/pubmed/36038778
http://dx.doi.org/10.1038/s43018-022-00416-8