The HASTER lncRNA promoter is a cis-acting transcriptional stabilizer of HNF1A

The biological purpose of long non-coding RNAs (lncRNAs) is poorly understood. Haploinsufficient mutations in HNF1A homeobox A (HNF1A), encoding a homeodomain transcription factor, cause diabetes mellitus. Here, we examine HASTER, the promoter of an lncRNA antisense to HNF1A. Using mouse and human m...

Descripción completa

Detalles Bibliográficos
Autores principales: Beucher, Anthony, Miguel-Escalada, Irene, Balboa, Diego, De Vas, Matías G., Maestro, Miguel Angel, Garcia-Hurtado, Javier, Bernal, Aina, Gonzalez-Franco, Roser, Vargiu, Pierfrancesco, Heyn, Holger, Ravassard, Philippe, Ortega, Sagrario, Ferrer, Jorge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9586874/
https://www.ncbi.nlm.nih.gov/pubmed/36202974
http://dx.doi.org/10.1038/s41556-022-00996-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9586874/
https://www.ncbi.nlm.nih.gov/pubmed/36202974
http://dx.doi.org/10.1038/s41556-022-00996-8

Ejemplares similares