Native chemical ligation approach to sensitively probe tissue acyl-CoA pools

During metabolism, carboxylic acids are often activated by conjugation to the thiol of coenzyme A (CoA). The resulting acyl-CoAs comprise a group of ∼100 thioester-containing metabolites that could modify protein behavior through non-enzymatic N-acylation of lysine residues. However, the importance...

Descripción completa

Detalles Bibliográficos
Autores principales: James, Andrew M., Norman, Abigail A.I., Houghton, Jack W., Prag, Hiran A., Logan, Angela, Antrobus, Robin, Hartley, Richard C., Murphy, Michael P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2022
Materias:
Resource
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9586882/
https://www.ncbi.nlm.nih.gov/pubmed/35868236
http://dx.doi.org/10.1016/j.chembiol.2022.04.005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9586882/
https://www.ncbi.nlm.nih.gov/pubmed/35868236
http://dx.doi.org/10.1016/j.chembiol.2022.04.005

Ejemplares similares