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Structure of the pre-mRNA leakage 39-kDa protein reveals a single domain of integrated zf-C3HC and Rsm1 modules

In Saccharomyces cerevisiae, the pre-mRNA leakage 39-kDa protein (ScPml39) was reported to retain unspliced pre-mRNA prior to export through nuclear pore complexes (NPCs). Pml39 homologs outside the Saccharomycetaceae family are currently unknown, and mechanistic insight into Pml39 function is lacki...

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Detalles Bibliográficos
Autores principales: Hashimoto, Hideharu, Ramirez, Daniel H., Lautier, Ophélie, Pawlak, Natalie, Blobel, Günter, Palancade, Benoît, Debler, Erik W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9586977/
https://www.ncbi.nlm.nih.gov/pubmed/36271106
http://dx.doi.org/10.1038/s41598-022-22183-3