The cholesterol transport protein GRAMD1C regulates autophagy initiation and mitochondrial bioenergetics

During autophagy, cytosolic cargo is sequestered into double-membrane vesicles called autophagosomes. The contributions of specific lipids, such as cholesterol, to the membranes that form the autophagosome, remain to be fully characterized. Here, we demonstrate that short term cholesterol depletion...

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Detalles Bibliográficos
Autores principales: Ng, Matthew Yoke Wui, Charsou, Chara, Lapao, Ana, Singh, Sakshi, Trachsel-Moncho, Laura, Schultz, Sebastian W., Nakken, Sigve, Munson, Michael J., Simonsen, Anne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9586981/
https://www.ncbi.nlm.nih.gov/pubmed/36270994
http://dx.doi.org/10.1038/s41467-022-33933-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9586981/
https://www.ncbi.nlm.nih.gov/pubmed/36270994
http://dx.doi.org/10.1038/s41467-022-33933-2

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