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The cholesterol transport protein GRAMD1C regulates autophagy initiation and mitochondrial bioenergetics
During autophagy, cytosolic cargo is sequestered into double-membrane vesicles called autophagosomes. The contributions of specific lipids, such as cholesterol, to the membranes that form the autophagosome, remain to be fully characterized. Here, we demonstrate that short term cholesterol depletion...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9586981/ https://www.ncbi.nlm.nih.gov/pubmed/36270994 http://dx.doi.org/10.1038/s41467-022-33933-2 |