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WASH activation controls endosomal recycling and EGFR and Hippo signaling during tumor-suppressive cell competition

Cell competition is a conserved homeostatic mechanism whereby epithelial cells eliminate neighbors with lower fitness. Cell communication at the interface of wild-type “winner” cells and polarity-deficient (scrib(−/−)) “losers” is established through Sas-mediated Ptp10D activation in polarity-defici...

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Detalles Bibliográficos
Autores principales: Liu, Dan, Tsarouhas, Vasilios, Samakovlis, Christos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9587002/
https://www.ncbi.nlm.nih.gov/pubmed/36271083
http://dx.doi.org/10.1038/s41467-022-34067-1